Pipeline

Mode of action Product Candidate / PROGRAM Drug substance Indication Discovery Pre-clinical Phase 1 Phase 2 Phase 3/ Pivotal Commercial Rights
Cancer Metabolism Tumor Starvation eryaspase (GRASPA® (1)) Asparaginase PDAC 2L
PDAC 1L
TNBC 1L
Solid tumor
TBD
Enzyme therapies Methionine-γ-lyase Solid tumors  
Enzyme therapies ERYZYME Therapeutic enzymes Metabolic diseases  
Immunotherapy ERYMMUNE Tumor antigens TBD  

Arrow indicates most advanced study within an indication or program; more detail is provided in subsequent slides
(1) Brand name for eryaspase in Europe and Israel

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