Pipeline

Mode of action Product Candidate / Program Drug substance Indication Discovery Pre-clinical Phase I Phase II Phase III / Pivotal EMA/FDA REVIEW Commercial Rights
Cancer Metabolism Tumor Starvation eryaspase (GRASPA® (1)) Asparaginase ALL EU

Europe

Israel

US and RoW

US
AML EU then EU/US
Pancreatic Cancer EU then EU/US
NH-Lymphoma Global  
erymethionase Methionine-γ-lyase Solid tumors  
eryminase Arginine deiminase Solid tumors  
Immunotherapy ERYMMUNE Tumor antigens TBD  
Enzyme therapies ERYZYME Therapeutic enzymes Metabolic diseases  

(1) Brand name for eryaspase in Europe and Israel

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