eryaspase

Product Candidate / PROGRAM Drug substance Indication Discovery Pre-clinical Phase 1 Phase 2 Phase 3/ Pivotal Commercial Rights
eryaspase (GRASPA® (1)) Asparaginase PDAC 2L
PDAC 1L
TNBC 1L
Solid tumor TBD

ERYTECH’s lead product candidate eryaspase, L-asparaginase encapsulated inside a donor-derived red blood cell, is a novel product candidate aimed at targeting cancer cells’ altered amino acid metabolism. L-asparaginase is well-established in the treatment of acute lymphoblastic leukemia, but toxicity has prevented its use in the most fragile patients and in other indications.

By encapsulating the L-asparaginase into red blood cells, eryaspase aims to enlarge its therapeutic window, and broaden the scope to other oncology indications such as pancreatic cancer and triple-negative breast cancer.

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